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Professional Focus

Before moving to California, Dr. Barbara Fowble was Clinical Director of the Radiation Oncology Department, Associate director of the Breast Evaluation Center and a Senior Member of the division of medical science at Fox Chase Cancer Center in Philadelphia, Pennsylvania. She is internationally recognized for her expertise in radiation and breast cancer. Dedicated to the treatment of breast cancer patients, Dr. Fowble has treated more than 2000 women with radiation. Her research studies have defined the roles of breast conservation therapy as an alternative to mastectomy and radiation after mastectomy. She was the founder and inspiration for the Fox Chase Cancer Center Complementary Medicine Program, “Complete Care”. Dr. Fowble has been selected as one of the top physicians in the United States by such publications as American Health Magazine, Best Doctors in America, Good Housekeeping, Town and Country and Philadelphia Magazine. She was featured in Time-Life’s medical video on breast cancer. Women with breast cancer have traveled across the United States and from other countries to consult with her. She is the author of numerous scientific publications and was the primary editor of a major textbook on breast cancer treatment. She has served on the editorial boards of the Journal of Clinical Oncology and the International Journal of Radiation Oncology, Biology and Physics and was a guest editor for Breast Disease: A Yearbook Quarterly and associate editor for The Breast Journal.

Awards & Honors

Publications

Fowble, B.: The Significance of Resection Margin Status in Patients with Early-Stage Invasive Cancer Treated with Breast-Conservation Therapy. The Breast Journal 4:126-131, 1998.

Freedman, G.M., Fowble, B.L., Hanlon, A.L., Myint, M.A., Hoffman, J.P., Sigurdson, E.R., Eisenberg, B.L., Goldstein, L.J., Fein, D.A.: A Close or Positive Margin After Mastectomy is Not an Indication for Chest Wall Irradiation Except in Women Aged Fifty or Younger. International Journal of Radiation Oncology, Biology, Physics 41:599-605, 1998.

Das, I.J., Cheng, E.C., Freedman, G., Fowble, B.: Lung and Heart Dose Volume Analyses with CT Simulator in Radiation Treatment of Breast Cancer. International Journal of Radiation Oncology, Biology, Physics 42:11-19, 1998.

Recht, A., Bartelink, H., Fourquet, A., Fowble, B., Harris, J.R., Kurtz, J., McCormick, B., Olivotto, I.A., Rutqvist, L., Solin, L.J., Yarnold, J.: Postmastectomy Radiotherapy: Questions for the Twenty-First Century. Journal of Clinical Oncology 16:2886-2889, 1998.

Hadley, D., Fowble, B., Torosian, M.H.: Evidence for Selective Use of Bone Scans in Early Stage Breast Cancer. Oncology Reports 5:991-993, 1998.

Fowble, B.; Hanlon, A.L., Patchefsky, A., Freedman, G., Hoffman, J.P., Sigurdson, E.R., Goldstein, L.J.: The Presence of Proliferative Breast Disease with Atypia Does Not Significantly Influence Outcome in Early Stage Invasive Breast Cancer Treated with Conservative Surgery and Radiation. International Journal of Radiation Oncology, Biology, Physics 42:105-115, 1998.

Montgomery, R.C., Fowble, B.L., Goldstein, L.J., May, D.P., Hoffman, J.P., Sigurdson, E.R., Eisenberg, B.L.: Local Recurrecne After Mastectomy for Ductal Carcinoma In Situ. The Breast Journal 4:430-436, 1998.

Fowble, B., Hanlon, A., Freedman, G., Patchefsky, A., Kessler, H., Nicolaou, N., Hoffman, J., Sigurdson, E., Boraas, M., Goldstein, L.: Postmenopausal Hormone Replacement Therapy (HRT):  Effect on Diagnosis and Outcome in Early Stage Invasive Breast Cancer Treated with Conservative Surgery and Radiation. Journal of Clinical Oncology 17:1680-1688, 1999.

Recht, A., Gray, R., Davidson, N.E., Fowble, B.L., Solin, L.J., Cummings, F.J., Falkson, G., Falkson, H.C., Taylor IV, S.G., Tormey, D.C.: Local-Regional Failure Ten Years Following Mastectomy and Adjuvant Chemotherpy With or Without Tamoxifen Without Irradiation:  Experience of the Eastern Cooperative Oncology Group. Journal of Clinical Oncology 17:1689-1700, 1999.

Fowble, B.: Postmastectomy Radiation in patients with One to Three Positive Axillary Nodes Receiving Adjuvant Chemotherapy:  An Unresolved Issue. Seminars in Radiation Oncology 9:1-12, 1999.

Freedman, G., Fowble, B., Hanlon, A., Fein, D., Nicolaou, N., Hoffman, J. Sigurdson, E., Boraas, M., Goldstein, L.: Patients with Early Stage Invasive Cancer with Close or Positive Margins Treated with Conservative Surgery and Radiation have an Increased Risk of Breast Recurrence that is Delayed by Adjuvant Systemic Therapy. International Journal of Radiation Oncology, Biology, Physics 44:1005-1015; 1999.

Fowble, B.: Ipsilateral Breast Tumor Recurrence Following Breast-Conserving Surgery for Early-Stage Invasive Cancer. Acta Oncologica 38:9-17, 1999.

Freedman, G.M., Fowble, B.L., Nicolaou, N., Sigurdson, E.R., Torosian, M.H., Boraas, M.C., Hoffman, J.P.: Should Internal Mammary Lymph Nodes in Breast Cancer a Target for the Radiation Oncologist? International Journal of Radiation Oncology, Biology, Physics 46:805-814, 2000.

Padmore, R.F., Fowble, B., Hoffman, J., Rosser, C., Hanlon, A., Patchefsky, A.S.: Microinvasive Breast Carcinoma Clinicopathologic Analysis of a Single Institution Experience. Cancer 88:1403-1409, 2000.

Fowble, B., Hanlon, A., Freedman, G., Nicolaou, N., Hoffman, J., Sigurdson, E., Boraas, M., Torosian, M., Goldstein, L.: Internal Mammary Node Irradiation Does Not Decrease Distant Metastases or Improve Survival in Stage I and II Breast Cancer. International Journal of Radiation Oncology, Biology, Physics 47:883-894, 2000.

Iyer, R.V., Hanlon, A., Fowble, B., Freedman, G., Nicolaou, N., Anderson, P., Hoffman, J., Sigurdson, E., Boraas, M., Torosian, M.: Accuracy of the Extent of Axillary Nodal Positivity Related to Primary Tumor Size, Number of Involved Nodes, and Number of Nodes Examined. International Journal of Radiation Oncology, Biology, Physics 47:1177-1183, 2000.

Freedman, G.M., Fowble, B.L.: Local Recurrence after Mastectomy or Breast-Conserving Surgery and Radiation.  Oncology, 14:1561-81, 2000.

Sasson, A.R., Fowble, B., Hanlon, A.L., Torosian, M.H., Freedman, G., Boraas, M., Sigurdson, E.R., Hoffman, J.P., Eisenberg, B.L., Patchefsky, A.:  Lobular Carcinoma in Situ Increases the Risk of Local Recurrence in Selected Patients with Stages I and II Breast Cancer Treated with Conservative Surgery and Radiation. Cancer, 91:1862-9, 2001.

Fowble, B., Hanlon, A., Freedman, G., Nicolaou, N., Anderson, P.: Second Cancers after Conservative Surgery and Radiation for Stages I-II Breast Cancer: Identifying a Subset of Women at Increased Risk. International Journal of Radiation Oncology Biology, Physics, 51: 679-690, 2001.

Chao, C., Torosian, M.H., Boraas, M.C., Sigurdson, E.R., Hoffman, J.P., Eisenberg, B.L. Fowble, B. Local Recurrence of Breast Cancer in the Stereotactic Core Needle Biopsy Site: Case Reports and Review of the Literature. The Breast Journal, 7:124-127, 2001.

Movsas, B., Li, B.S.Y., Babb, J.S., Fowble, B.L., Nicolaou, N., Gonen, O.: Quantifying Radiation Therapy-induced Brain Injury with Whole-Brain Proton MR Spectroscopy:  Initial Observations. Radiology, 221:327-331, 2001

Morrow, M., Strom, E.A., Bassett, L.W., Dershaw, D.D., Fowble, B., Harris, J.R., O’Malley,F., Schnitt, S.J., Singletary, S.E., Winchester, D.P.: Standard for the Management of Ductal Carcinoma In Situ of the Breast. CA Cancer J Clin, 52:256-276, 2002.

Morrow, M., Strom, E.A., Bassett, L.W., Dershaw, D.D., Fowble, B., Giuliano, A., Harris, J.R., O’Malley, F., Schnitt, S.J., Singletary, S.E., Winchester, D.P.: Standard for Breast Conservation Therapy in the Management of Invasive Breast Carcinoma. CA Cancer J Clin, 52:277-300, 2002.

Freedman, G. M., Hanlon, A.L., Fowble, B.L., Anderson, P.R., Nicolaou, N.: Recursive Partitioning Identifies Patients at High and Low Risk for Ipsilateral Tumor Recurrence after Breast Conserving Surgery and Radiation. J Clinical Oncology, 20: 4015-4021, 2002.

Anderson, P.R., Hanlon, A.L., Fowble, B., McNeely, S.W., Freedman, G.M.: Low complication rates are achievable after postmastectomy breast reconstruction and radiation therapy. International Journal of Radiation Oncology Biology and Physics, 59:1080-1087, 2004.