• Publications
• Experience
• About

Professional Focus

Dr. I-Chow (Joe) Hsu is an expert in brachytherapy, the treatment that involves placing radiation material directly into or near a tumor. Hsu specializes in the treatment of genitourinary, gynecological, head and neck and soft tissue tumors. He is interested in the development of minimally invasive implant procedures and precision delivery of conformal high dose rate brachytherapy and hyperthermia. He earned his medical degree from Johns Hopkins School of Medicine and completed a residency in radiation oncology at Columbia-Presbyterian Medical Center.

Education

1987	University of Florida, Gainesville	BS	Biochemistry
1991	The Johns Hopkins School of Medicine, Baltimore	MD
1991-1992	San Bernardino County Medical Center, San Bernardino	Intern
1992-1995	Columbia-Presbyterian Medical Center, New York	Resident	Radiation Oncology
1994-1995	Columbia-Presbyterian Medical Center, New York	Chief Resident	Radiation Oncology

Professional Experience

2010-present	University of California, San Francisco	Professor Clinical X Series	Radiation Oncology
2010-present	University of California, San Francisco	Chief of Clinical Services at HDFCCC	Radiation Oncology
2007-present	University of California, San Francisco	Vice Chair	Radiation Oncology
2004-2010	University of California, San Francisco	Associate Professor Clinical X Series	Radiation Oncology
1998-2004	University of California, San Francisco	Assistant Professor Clinical X Series	Radiation Oncology
1997-1998	University of California, San Francisco	Assistant Clinical Professor	Radiation Oncology
1995-1997	California Endocurietherapy Cancer Center, Oakland, CA	Radiation Oncologist	Radiation Oncology

Awards & Honors

1987	Magna cum Laude
1988	Dean's Fund for Research
1989	The John Scott McFarland Fund for Research
1990	Dean's Fund for Research
1991	Accolade for Outstanding Intern
2006	ARRO Teacher of the year
2008	ARRO Teacher of the year
2008	Lawrence Margolis Lifetime Teaching Award
2008	Nominated by Medical Student Class of 2008 for Alpha Omega Alpha membership in the alumni category at the UCSF
2009	ARRO Teacher of the Year
2010	Fellow of American College of Radiology
2009-2011	Best Doctors in America®

Recent Significant Publications

Cury FL, Hunt D, Roach M 3rd, Shipley W, Gore E, Hsu IC, Krisch RE, Seider MJ, Sandler H, Lawton C. Prostate-specific antigen response after short-term hormone therapy plus external-beam radiotherapy and outcome in patients treated on Radiation Therapy Oncology Group study 9413,Cancer. 2013 Mar 15.

Chen CP, Weinberg V, Shinohara K, Roach M 3rd, Nash M, Gottschalk A, Chang AJ, Hsu IC., Salvage HDR Brachytherapy for Recurrent Prostate Cancer After Previous Definitive Radiation Therapy: 5-Year Outcomes, Int J Radiat Oncol Biol Phys. 2013 Mar 5.

Hsu CC, Hsu H, Pickett B, Crehange G, Hsu IC, Dea R, Weinberg V, Gottschalk AR, Kurhanewicz J, Shinohara K, Roach M 3rd., Feasibility of MR imaging/MR spectroscopy-planned focal partial salvage permanent prostate implant (PPI) for localized recurrence after initial PPI for prostate cancer, Int J Radiat Oncol Biol Phys. 2013 Feb 1;85(2):370-7.

Pejavar S, Yom SS, Hwang A, Speight J, Gottschalk A, Hsu IC, Roach M, Xia P., Computer-Assisted, Atlas-Based Segmentation for Target Volume Delineation in Whole Pelvic IMRT for Prostate Cancer, Technol Cancer Res Treat. 2012 Dec 26.

Siauw T, Cunha A, Berenson D, Atamturk A, Hsu IC, Goldberg K, Pouliot J., NPIP: A skew line needle configuration optimization system for HDR brachytherapy, Med Phys. 2012 Jul;39(7):4339-46.

Li CY, Chiang CS, Cheng WC, Wang SC, Cheng HT, Chen CR, Shu WY, Tsai ML, Hseu RS, Chang CW, Huang CY, Fang SH, Hsu IC., Gene expression profiling of dendritic cells in different physiological stages under Cordyceps sinensis treatment, PLoS One. 2012;7(7):e40824.

Chen CS, Chung WJ, Hsu IC, Wu CM, Chin WC., Force field measurements within the exclusion zone of water, J Biol Phys. 2012 Jan;38(1):113-20.

Abdel-Wahab M, Mahmoud O, Merrick G, Hsu IC, Arterbery VE, Ciezki JP, Frank SJ, Mohler JL, Moran BJ, Rosenthal SA, Rossi CJ Jr, Yamada Y., ACR Appropriateness Criteria® external-beam radiation therapy treatment planning for clinically localized prostate cancer, J Am Coll Radiol. 2012 Apr;9(4):233-8.

Yamada Y, Rogers L, Demanes DJ, Morton G, Prestidge BR, Pouliot J, Cohen GN, Zaider M, Ghilezan M, Hsu IC; American Brachytherapy Society., American Brachytherapy Society consensus guidelines for high-dose-rate prostate brachytherapy, Brachytherapy. 2012 Jan-Feb;11(1):20-32.

Shiao SL, Sahgal A, Hu W, Jabbari S, Chuang C, Descovich M, Hsu IC, Gottschalk AR, Roach M 3rd, Ma L., Temporal compartmental dosing effects for robotic prostate stereotactic body radiotherapy., Phys Med Biol. 2011 Dec 21;56(24):7767-75.

Moran BJ, DeRose P, Hsu IC, Abdel-Wahab M, Arterbery VE, Ciezki JP, Frank SJ, Mohler JL, Rosenthal SA, Rossi CJ Jr, Yamada Y, Merrick GS., ACR Appropriateness Criteria® definitive external beam irradiation in stage T1 and T2 prostate cancer, Am J Clin Oncol. 2011 Dec;34(6):636-47.

Cunha JA, Pouliot J, Weinberg V, Wang-Chesebro A, Roach M 3rd, Hsu IC., Urethra low-dose tunnels: validation of and class solution for generating urethra-sparing dose plans using inverse planning simulated annealing for prostate high-dose-rate brachytherapy, Brachytherapy. 2012 Sep-Oct;11(5):348-53.

Ciezki JP, Hsu IC, Abdel-Wahab M, Arterbery VE, Frank SJ, Mohler JL, Moran BJ, Rosenthal SA, Rossi CJ, Yamada Y, Merrick G; American College of Radiology Appropriateness Criteria., American College of Radiology Appropriateness Criteria(®)--locally advanced (high-risk) prostate cancer, Clin Oncol (R Coll Radiol). 2012 Feb;24(1):43-51.

Siauw T, Cunha A, Atamtürk A, Hsu IC, Pouliot J, Goldberg K., IPIP: A new approach to inverse planning for HDR brachytherapy by directly optimizing dosimetric indices, Med Phys. 2011 Jul;38(7):4045-51.

Wootton JH, Prakash P, Hsu IC, Diederich CJ., Implant strategies for endocervical and interstitial ultrasound hyperthermia adjunct to HDR brachytherapy for the treatment of cervical cancer, Phys Med Biol. 2011 Jul 7;56(13):3967-84.

Expert Panel on Radiation Oncology-Prostate, Frank SJ, Arterbery VE, Hsu IC, Abdel-Wahab M, Ciezki JP, Hahn NM, Mohler JL, Moran BJ, Rosenthal SA, Rossi CJ, Yamada Y, Merrick G., American College of Radiology Appropriateness Criteria permanent source brachytherapy for prostate cancer, Brachytherapy. 2011 Sep-Oct;10(5):357-62.

Wootton JH, Hsu IC, Diederich CJ., Endocervical ultrasound applicator for integrated hyperthermia and HDR brachytherapy in the treatment of locally advanced cervical carcinoma, Med Phys. 2011 Feb;38(2):598-611.

Krishnamurthy D, Weinberg V, Cunha JA, Hsu IC, Pouliot J., Comparison of high-dose rate prostate brachytherapy dose distributions with iridium-192, ytterbium-169, and thulium-170 sources, Brachytherapy. 2011 Nov-Dec;10(6):461-5.

Jabbari S, Weinberg VK, Kaprealian T, Hsu IC, Ma L, Chuang C, Descovich M, Shiao S, Shinohara K, Roach M 3rd, Gottschalk AR., Stereotactic body radiotherapy as monotherapy or post-external beam radiotherapy boost for prostate cancer: technique, early toxicity, and PSA response, Int J Radiat Oncol Biol Phys. 2012 Jan 1;82(1):228-34.

Kaprealian T, Weinberg V, Speight JL, Gottschalk AR, Roach M 3rd, Shinohara K, Hsu IC., High-dose-rate brachytherapy boost for prostate cancer: comparison of two different fractionation schemes, Int J Radiat Oncol Biol Phys. 2012 Jan 1;82(1):222-7.

Erickson BA, Demanes DJ, Ibbott GS, Hayes JK, Hsu IC, Morris DE, Rabinovitch RA, Tward JD, Rosenthal SA., American Society for Radiation Oncology (ASTRO) and American College of Radiology (ACR) practice guideline for the performance of high-dose-rate brachytherapy, Int J Radiat Oncol Biol Phys. 2011 Mar 1;79(3):641-9.

Cunha JA, Hsu IC, Pouliot J, Roach Iii M, Shinohara K, Kurhanewicz J, Reed G, Stoianovici D., Toward adaptive stereotactic robotic brachytherapy for prostate cancer: demonstration of an adaptive workflow incorporating inverse planning and an MR stealth robot,Minim Invasive Ther Allied Technol. 2010 Aug;19(4):189-202.

Descovich, M., Speight, J., Aubin, M., Hsu, I-C., Chen, J., Aubry, J., Lometti, M., Pouliot J., Technical Note: Megavoltage Cone-Beam CT to Assist CT-Based Treatment Planning for HDR Brachytherapy, Medical Physics, In Press

Wootton, J., Hsu, I-C., Diederich, C., An Endocervical Ultrasound Applicator for Integrated Hyperthermia and HDR Brachytherapy in the Treatment of Locally Advanced Cervical Carcinoma, Med Physics, 2010, In Press

Kaprealian, T., Weinberg, V., Speight, J., Gottschalk, A., Roach, M., Shinohara, K., Hsu, I-C., High Dose Rate Brachytherapy Boost for Prostate Cancer: Comparison of Two Different Fractionation Schemes, International Jounral of Radiation Oncology Biology, Physics, 2010, In Press

Hsu, I-C., Bae, K., Shinohara, K., Pouliot, J., Purdy, J., Ibbott, G., Speight. J.,Vigneault, E., Ivker, R., Sandler, H., Phase II Trial of Combined High Dose Rate Brachytherapy and External Beam Radiotherapy for Adenocarcinoma of the Prostate: Preliminary Results of RTOG 0321, International Journal of Radiation Oncology, Biology, Physics 78:751-8, 2010 PMID:20207506, NIHMSID: NIHMS209285

Foster W, Cunha JA, Hsu I-C, Weinberg V, Krishnamurthy D, Pouliot J., Dosimetric Impact of Interfraction Catheter Movement in High-Dose Rate Prostate Brachytherapy. International Journal of Radiation Oncology, Biology, Physics, 2010 PMID:20605353

Cunha, A., Hsu, I-C., Pouliot, J. Roach, M. Shinohara, K. Kurhanewicz, Reed, G., Stoianovici, D., Toward Adaptive Stereotactic Robotic Brachytherapy for Prostate Cancer: Demonstration of an Adaptive Workflow Incorporating Inverse Planning and an MR Stealth Robot, Minim Invasive Ther Allied Technol 19(4):189-202, 2010 PMID: 20642386

Aubry, J., Beaulieu, L., Hsu, I-C., Pouliot, J., Investigation of geometric distortions on MR and CBCT images used for planning and verification of HDR brachytherapy cervical cancer treatment, Brachytherapy, 9(3):266-73, 2010 PMID:20149759

Stauffer, P., MacCarini, P., Arunachalam, K., Craciunescu, O., Diederich, C., Juang, T., Rossetto, F., Schlorff, J., Milligan, A., Hsu, I-C., Sneed, P., Vujaskovic, Z., Conformal Microwave Array (CMA) Applicator for Hyperthermia of Diffuse Chest Wall Recurrence, Internation journal of Hyperthermia, 26(7): 686-98, 2010 PMID:20849262

Chen, X., Diederich, C., Wootton, J., Pouliot, J., Hsu, I-C., Optimisation-based Thermal Treatment Planning for Catheter-based Ultrasound Hyperthermia, International Journal Hyperthermia, 26:39-55, 2010 PMID:20100052

Jabbari, S., Weinberg, V., Shinohara, S., Speight, J., Gottschalk, A., Hsu, I-C., Pickett, B., Mclaughlin, P., Sandler, H., Roach, M., Equivalent Biochemical Control And Improved Prostate-Specific Antigen Nadir After Permanent Prostate Seed Implant Brachytherapy Versus High-Dose Three-Dimensional Conformal Radiotherapy And High-Dose Conformal Proton Beam Radiotherapy Boost, International Journal Radiation Oncology Biol. Phys., Vol. 76, No. 1, Pp. 36–42, 2010 PMID 19409729

Jabbari, S., Hsu I-C., Kawakami, J., Weinberg, V., Speight, J., Gottschalk, A., Roach, M., Shinohara, K., High-Dose-Rate Brachytherapy for Localized Prostate Adenocarcinoma Post-Abdominoperineal Resection of the Rectum and Pelvic Irradiation: Technique and Experience, Brachytherapy 9:339-344, 2009 PMID:19428310

Kim, D. Wang-Chesebro1, A., Weinberg, V., Pouliot J., Chen L., Speight, J., R. Littell, R. Hsu, I-C., High Dose Rate Brachytherapy Using Inverse Planning Simulated Annealing for Loco-regionally Advanced Cervical Cancer: A Clinical Report with 2-Year Follow- Up, International Journal of Radiation Oncology, Biology, Physics, 75:1329-1334, 2009 PMID:19409728

Schmid, S., Hsu, I-C., Hu, J., Sherman, A., Osann, K., Kapp, D., Chan, J., Adjuvant Radiation Therapy in Stage III Node-positive Uterine Cancer, Gyn. Oncol. 115:239-243, 2009 PMID:19679341

Aaronson, D., Pickett, B., Gottschalk, A., Hsu, I-C., Roach, M., Shinohara, K., Salvage Permanent Perineal Radioactive Seed Implantation for the Treatment of Localized Prostate Adenocarcinoma Recurrence After External Beam Radiation, Br. J. Urol Int, 104 (5):600-4, 2009 PMID:19245439

Westphalen, A., Kurhanewicz, J., Cunha, RMG, Hsu, I-C., Kornak, J., Zhao, S., Coakley, FV. T2-weighted endorectal MR imaging of prostate cancer after external beam radiation therapy. Int Braz J Urol 35(2): 171-182, 2009 PMID:19409121

Joseph, T., McKenna, D. A., Westphalen, A. C., Coakley, F. V., Zhao, S., Lu, Y., Hsu, I- C., Roach, M., 3rd, Kurhanewicz, J., Pretreatment Endorectal Magnetic Resonance Imaging and Magnetic Resonance Spectroscopic Imaging Features of Prostate Cancer as Predictors of Response to External Beam Radiotherapy, International Journal of Radiation Oncology, Biology, Physics, 73(3): 665-671, 2009 PMID:18760545, PMCID: PMC2737354, NIHMSID: NIHMS125522

Alterovitz, R., Goldberg, K., Pouliot, J., Hsu, I-C., Sensorless Motion Planning for Medical Needle Insertion in Deformable Tissue, IEEE Transactions on Information Technology in Biomedicine, 13(2): 217-225, 2009 PMID:19126473, PMCID: PMC2822650, NIHMSID:NIHMS107206

Cunha, A., Hsu, I-C., Pouliot, J., Dosimetric Equivalence of Non-standard HDR Brachytherapy Catheter Patterns, Medical Physics 36 (1): 233-239, 2009 PMID19235391

Kubicky C., Yeh B., Lessard, E., Joe, B., Speight J., Pouliot J., Hsu, I-C., Inverse Planning for the Magnetic Resonance Imaging (MRI)-Based Intracavitary High Dose Rate (HDR) Brachytherapy for Cervical Cancer: A Feasibility Study, In press, Brachytherapy.

Kim, Y., Hsu, I-C., Lessard, E., Kurhanewicz, J., Noworolski, S., Pouliot, J., Class Solution in Inverse Planned HDR Prostate Brachytherapy for Dose Escalation of DIL Defined by Combined MRI/MRSI, Radiotherapy and Oncology, 88:148-55, 2008 PMID: 18083260

Sahgal, A. Jabbari, S., Chen, J., Pickett, B., Roach, M., Weinberg, V., Hsu, I-C., Pouliot, J. Comparison of Dosimetric and Biologic Effective Dose Parameters for Prostate and Urethra Using 131Cs and 125I for Prostate Permanent Implant Brachytherapy, International Journal of Radiation Oncology, Biology, Physics, 72:247-254, 2008 PMID: 18722275

Chan, L., Xia, P., Gottschalk, A., Akazawa, M., Scala, M., Pickett, B., Hsu, I-C., Speight J. Roach, M., Proposed Rectal Dose Constraints for Patients Undergoing Definitive Whole Pelvis Radiation Therapy for Clinically Localized Prostate Cancer, International Journal of Radiation Oncology, Biology, Physics, 72:69-77, 2008 PMID:18342454

Kim, Y., Hsu, I-C., Pouliot, J.  Cranio-Caudal Catheter Displacement Between Fractions in CT-Based HDR Brachytherapy of Prostate Cancer, Journ. of Applied Clinical Med. Phys. 8 (4): 1-13; 2007.

Lee, B., Shinohara, K., Weinberg, V., Gottschalk, A., Pouliot, J., Roach, M., Hsu, I-C, High Dose Rate (HDR) Brachytherapy Salvage for Local Prostate Recurrence After Radiotherapy: The UCSF Experience, International Journal of Radiation Oncology, Biology, 67(4):1106-1112, 2007.

Schiffner, D., Gottschalk, A., Lometti, M., Aubin, M., Pouliot, J., Speight, J., Hsu, I-C., Shinohara, K.,Roach, M., Daily Electronic Portal Imaging of Implanted Gold Seed Fiducials in Patients Undergoing Radiotherapy After Radical Prostatectomy, International Journal of Radiation Oncology, Biology, 67:610-619, 2007.

Alterovitz, R., Lessard, E., Pouliot, J., Hsu, I-C., O'Brien, J., Goldberg, K., Optimization of HDR Brachytherapy Dose Distributions Using Linear Programming with Penalty Costs, Medical Physics, 33(11);4012-4019, 2006.

Alterovitz, R., Goldberg, K., Pouliot, J., Hsu, I-C., Kim, Y., Noworolski, S., Kurhanewicz, J., Registration of MR Prostate Images with Biomechanical Modeling and Nonlinear, Parameter Estimation, Medical Physics, 33(2):446-454, 2006.

I-Chow Joe Hsu22. Sumida I., Shiomi H., Yoshioka Y., Inoue T., Lessard E., Hsu I-C., Pouliot J., Optimization of Dose Distribution For HDR Brachytherapy of the Prostate Using Attraction-Repulsion Model, International Journal of Radiation Oncology Biology Physics 64(2):643-649; 2006.

Sumida I., Shiomi H., Yoshioka Y., Inoue T., Lessard E., Hsu I-C., Pouliot J., Optimization of Dose Distribution For HDR Brachytherapy of the Prostate Using Attraction-Repulsion Model, International Journal of Radiation Oncology Biology Physics 64(2):643-649; 2006.

Alterovitz, R., Goldberg, K., Pouliot, J., Hsu, I-C., Kim, Y., Moyher-Nowolski, S., Kurhanewicz, J., Registration of MR Prostate Images with Biochemical Modeling and Nonlinear Parameter Estimation, Medical Phyicss, 33( 2):446-454, 2006.

 

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