Dr. Catherine Park is a radiation oncologist with a special interest in the treatment of lymphoma and breast cancer. She earned a medical degree at the UCLA School of Medicine and completed a residency in radiation oncology at the Joint Center for Radiation Oncology at Harvard Medical School. After serving as a visiting scientist at the Lawrence Berkeley National Laboratory, Park joined UCSF Medical Center.
She is the recipient of numerous awards, including the Upjohn Achievement Award and C. Donald O'Malley Prize in the History of Medicine.
Awards & Honors
Recent Significant Publications
Park CC, Georgescu W, Polyzos A, Pham C, Ahmed KM, Zhang H, Costes SV. Rapid and automated multidimensional fluorescence microscopy profiling of 3D human breast cultures. Integr Biol (Camb). 2013 Apr 25;5(4):681-91.
Peled AW, Foster RD, Esserman LJ, Park CC, Hwang ES, Fowble B. Increasing the time to expander-implant exchange after postmastectomy radiation therapy reduces expander-implant failure. Plast Reconstr Surg. 2012 Sep;130(3):503-9.
Wang RT, Ahn S, Park CC, Khan AH, Lange K, Smith DJ. Effects of genome-wide copy number variation on expression in mammalian cells. BMC Genomics. 2011 Nov 16;12:562.
Huang C, Park CC, Hilsenbeck SG, Ward R, Rimawi MF, Wang YC, Shou J, Bissell MJ, Osborne CK, Schiff R.?1 integrin mediates an alternative survival pathway in breast cancer cells resistant to lapatinib. Breast Cancer Res. 2011 Aug 31;13(4):R84.
Ghazalpour A, Bennett B, Petyuk VA, Orozco L, Hagopian R, Mungrue IN, Farber CR, Sinsheimer J, Kang HM, Furlotte N, Park CC, Wen PZ, Brewer H, Weitz K, Camp DG 2nd, Pan C, Yordanova R, Neuhaus I, Tilford C, Siemers N, Gargalovic P, Eskin E, Kirchgessner T, Smith DJ, Smith RD, Lusis AJ. Comparative analysis of proteome and transcriptome variation in mouse. PLoS Genet. 2011 Jun;7(6):e1001393.
Nabavizadeh N, Klifa C, Newitt D, Lu Y, Chen YY, Hsu H, Fisher C, Tokayasu T, Olshen AB, Spellman P, Gray JW, Hylton N, Park CC. Topographic enhancement mapping of the cancer-associated breast stroma using breast MRI..Integr Biol (Camb). 2011 Apr;3(4):490-6.
Nam JM, Onodera Y, Bissell MJ, Park CC.Breast cancer cells in three-dimensional culture display an enhanced radioresponse after coordinate targeting of integrin alpha5beta1 and fibronectin. Cancer Res. 2010 Jul 1;70(13):5238-48.
Lin A, Wang RT, Ahn S, Park CC, Smith DJ.A genome-wide map of human genetic interactions inferred from radiation hybrid genotypes. Genome Res. 2010 Aug;20(8):1122-32.
Park CC, Yom SS, Podgorsak MB, Harris E, Price RA Jr, Bevan A, Pouliot J, Konski AA, Wallner PE; Electronic Brachytherapy Working Group.American Society for Therapeutic Radiology and Oncology (ASTRO) Emerging Technology Committee report on electronic brachytherapy.Int J Radiat Oncol Biol Phys. 2010 Mar 15;76(4):963-72.
Weigelt B, Lo AT, Park CC, Gray JW, Bissell MJ.HER2 signaling pathway activation and response of breast cancer cells to HER2-targeting agents is dependent strongly on the 3D microenvironment. Breast Cancer Res Treat. 2010 Jul;122(1):35-43.
Nam JM, Chung Y, Hsu HC, Park CC. beta1 integrin targeting to enhance radiation therapy. Int J Radiat Biol. 2009 Nov;85(11):923-8.
Ahn S, Wang RT, Park CC, Lin A, Leahy RM, Lange K, Smith DJ. Directed mammalian gene regulatory networks using expression and comparative genomic hybridization microarray data from radiation hybrids. PLoS Comput Biol. 2009 Jun;5(6):e1000407.
Park CC, Rembert J, Chew K, Moore D, Kerlikowske K.High mammographic breast density is independent predictor of local but not distant recurrence after lumpectomy and radiotherapy for invasive breast cancer. Int J Radiat Oncol Biol Phys. 2009 Jan 1;73(1):75-9.
Park CC, Zhang HJ, Yao ES, Park CJ, Bissell MJ.Beta1 integrin inhibition dramatically enhances radiotherapy efficacy in human breast cancer xenografts. Cancer Res. 2008 Jun 1;68(11):4398-405.
Park CC, Zhang HJ, Yao ES, Kim S, Park CJ, Bissell MJ. Inhibition of B1 integrin enhances breast cancer radiotherapy. Cancer Res. 2008 Jun 1;68(11):4398-405.
Park CC, Ahn S, Bloom JS, Lin A, Wang RT, Wu T, Sekar A, Khan AH, Farr CJ, Lusis AJ, Leahy RM, Lange K, Smith DJ.Fine mapping of regulatory loci for mammalian gene expression using radiation hybrids..Nat Genet. 2008 Apr;40(4):421-9.
Park CC, Rembert JR, Chew K, Moore DM, Kerlikowske K. High mammographic breast density and obesity are associated with increased local recurrence following lumpectomy and radiation therapy for invasive breast cancer. Int J Radiat Oncol Biol Phys. 2008 Aug 7.
Rembert J, Klifa C, Lu Y, Gibbs J, Hylton N, Park CC, Stromal Enhancement by MRI is Associated with Response to Neoadjuvant Chemotherapy. AJR 2008 Jun;190(6):1630-6.
Yao ES, Lee B, Chen YY, Moore D, Park CC.High B1 integrin over-expression is associated with poor overall survival in breast cancer patients. Cancer Res 2007; 67: (2). January 15, 2007.
Chang H, Park C, and Parvin B. Quantitative Representation of Three-dimensional Cell Culture Models. 2007 IEEE International Symposium on Biomedical Imaging, February 2007.
Park CC and Cordes N. B1 integrin as a molecular therapeutic target. Int J Radiat Biol. 2007 Nov-Dec;83(11-12):753-60.
Books and Chapters
Park CC and Esserman, LJ. Ductal Carcinoma In Situ, A Modern Approach. Ductal Carcinoma in Situ. Ed., Solin et. al., first edition, in press, 2005.
Park CC, Schnitt SJ, Recht A. Management of DCIS, The JCRT Experience. Ductal Carcinoma in Situ of the Breast. Ed., Silverstein et. al., second edition, 2002.
Henshall-Powell R, Park CC, Barcellos-Hoff MH. Aberrant extracellular signaling induced by ionizing radiation and its role in carcinogenesis. International Congress Series 742 (2001).
Invited Feature Commentary