• Publications
• Experience
• About

Professional Focus

Dr. Theodore Phillips is a radiation oncologist and a renowned expert in ocular melanoma, gamma knife and intra-operative radiotherapy. He is the recipient of numerous awards and has served as president of various medical and scientific associations, including the Radiation Research Society, American Society for Therapeutic Radiology and Oncology and the North American Hyperthermia Society. He earned a medical degree from the University of Pennsylvania School of Medicine in Philadelphia and completed a residency in radiation oncology at the University of California, San Francisco. He holds the position of the Wun-Kon Fu distinguished professor of radiation oncology at UCSF and is a member of the Institute of Medicine of the National Academy of Sciences.

Education

Professional Experience

Awards & Honors

Publications

Lee DJ, Phillips TL, Coleman CN, Cosmatos D, Davis LW, Wasserman TH, Marcial VA, Rubin P. Logistics in designing clinical trials for etanidazole (SR 2508): An RTOG experience. Int J Radiat Oncol Biol Phys ,22:569-571, 1992.

Nowakowski VA, Castro JR, Petti PL, Collier JM, Daftari I, Ahn D, Gauger G, Gutin P, Linstadt DE, Phillips TL. Charged particle radiotherapy of paraspinal tumors. Int J Radiat Oncol Biol Phys, 22:295-303, 1992.

Prados MD, Gutin PH, Phillips TL, Wara WM, Larson DA, Sneed PK, Davis RL, Ahn DK, Lamborn K, Wilson CB. Highly anaplastic astrocytoma: a review of 357 patients treated between 1977 and 1989. Int J Radiat Oncol Biol Phys , 23:3-8, 1992.

Sneed PK, Gutin PH, Stauffer PR, Phillips TL, Prados MD, Weaver KA, Suen S, Lamb SA, Ham B, Ahn DK, et al. Thermoradiotherapy of recurrent malignant brain tumors. Int J Radiat Oncol Biol Phys , 23:853-861, 1992.

Schoenthaler R, Albright NW, Wara WM, Phillips TL, Wilson CB, Larson DA. Re-irradiation of pituitary adenomas. Int J Radiat Oncol Biol Phys, 24:307-14, 1992.

Sneed PK, Gutin PH, Prados MD, Phillips TL, Weaver KA, Wara WM, Larson DA. Brachytherapy of brain tumors. Stereotact Funct Neurosurg, 59:157-165, 1992.

Scharfen CO, Sneed PK, Wara WM, Larson DA, Phillips TL, Prados MD, Weaver KA, Malec M, Lamborn KR, Lamb SA, Ham B, Gutin PH. High activity Iodine-125 interstitial implant for gliomas. Int J Radiat Oncol Biol Phys , 24:583-591, 1992.

Prados MD, Gutin PH, Phillips TL, Wara WM, Sneed PK, Larson DA, Lamb SA, Ham B, Malec MK, Wilson CB. Interstitial brachytherapy for newly diagnosed patients with malignant gliomas: The UCSF experience. Int J Radiat Oncol Biol Phys, 24:593-597,1992.

Curran WJ Jr., Scott CB, Nelson JS, Weinstein AS, Phillips TL, Murray K, Fischbach AJ, Yakar D, Schwade JG, Powlis WD, Nelson DF. A randomized trial of accelerated hyperfractionated radiation therapy and bis-chlorethyl nitrosourea for malignant glioma. Cancer, 70:2909-2917, 1992.

Swift PS, Phillips T, Martz K, Wara W, Mohiuddin M, Chang CH, Asbell So. CT characteristics of patients with brain metastases treated in RTOG study 79-16. Int J Radiat Oncol Biol Phys, 25:209-214, 1993.

Hricak H, Quivey JM, Campos Z, Gildengorin V, Hindmarsh T, Kostake GB, Stern JL, Phillips TL. Carcinoma of the cervix: Predictive value of clinical and magnetic resonance (MR) imaging assessment of prognostic factors. Int J Radiat Oncol Biol Phys, 27:791-801, 1993.

Curran WJ, Scott CB, Weinstein AS, Martin LA, Nelson JS, Phillips TL, Murray K, Fischbach AJ, Yakar D, Schwade JG, Corn B, Nelson DF. Survival comparison of radiosurgery-eligible and -ineligible malignant glioma patients treated with hyperfractionated radiation therapy and carmustine: A report of Radiation Therapy Oncology Group 83-02. Jrnl Clin Oncol, 11(5):857-862, 1993.

Schoenthaler R, Castro JR, Petti PL, Baken-Brown, K, Phillips TL. Charged particle irradiation of sacral chordomas. Int J Radiat Oncol Biol Phys ,26:291-298, 1993.

Mack CF, Stea B, Kittelson JM, Shimm DS, Sneed PK, Phillips TL, Swift PS, Luk K, Stauffer PR, Chan KW, Steeves R, Cassady JR, Cetas TC. Interstitial thermoradiotherapy with ferromagnetic implants for locally advanced and recurrent neoplasms. Int J Radiat Oncol Biol Phys, 27:109-115, 1993.

Roach M, Pickett B, Rosenthal S,A Verhey L, Phillips TL. Defining treatment margins for six field conformal irradiation of localized prostate cancer. Int J Radiat Oncol Biol Phys, 28:267-275, 1994.

Kaplan ID, Castro JR, Phillips TL. Helium charged particle radiotherapy for meningioma: Experience at UCLBL. Int J Radiat Oncol Biol Phys, 28:257-261, 1994.

Huang SK, Stauffer PR, Hong K, Guo JWH, Phillips TL, Huang A, Papahadjopoulos D. Liposomes and hyperthermia in mice: Increased tumor uptake and therapeutic efficacy of doxorubicin in sterically stabilized liposomes. Cancer Research, 54:2186-2191, 1994.

Castro JR, Linstadt DE, Bahary JP, Petti PP, Daftari I, Collier M, Gutin PH, Gauger G, Phillips TL. Experience in charged particle irradiation of tumor of the skull base: 1977-1992. Int J Radiat Oncol Biol Phys, 29:647-655, 1994.

Sneed PK, Gutin PH, Malec MK, Phillips TL, Prados MD, Scharfen CO, Weaver KA, Wara W. Patterns of recurrence of glioblastoma multiforme after external irradiation followed by implant boost. Int J Radiat Oncol Biol Phys, 29:719-727, 1994.

Levin VA, Prados MD, Wara WM, Davis RL, Gutin PH, Phillips TL, Lamborn K, Wilson CB. Radiation therapy and bromodeoxyuridine chemotherapy followed by procarbazine, lomustine, and vincristine for the treatment of anaplastic gliomas. Int J Radiat Oncol Biol Phys, 32:75-83, 1995.

Pickett B, Roach M, Verhey L, Horine P, Malfatti C, Akazawa C, Dea D, Varad B, Rathbun C, Phillips TL. The value of nonuniform margins for six-field conformal irradiation of localized prostate cancer. Int J Radiat Oncol Biol Phys, 32:211-218, 1995.

Sneed PK, Prados MD, McDermott MW, Larson DA, Malec MK, Lamborn KR, Davis RL, Weaver KA, Wara WM, Phillips TL, Gutin PH. Large effect of age on the survival of patients with glioblastoma treated with radiotherapy and brachytherapy boost. Neurosurgery, 36:898-904, 1995.

Rubin P, Constine LS, Fajardo LF, Phillips TL, Wasserman T. Overview. Late effects of normal tissues (LENT) scoring system. Int. J. Radiation Oncology Biol Phys. 31(5): 1041-1042, 1995.

McDonald S, Rubin P, Phillips TL, Marks LB. Injury to the lung from cancer therapy: Clinical syndromes, measurable endpoints, and potential scoring systems. Int. J. Radiation Oncology Biol Phys. 31(5): 1187-1203, 1995.

Phillips TL, Scott CB, Leibel SA, Rotman M, Weigensberg IJ. Results of a randomized comparison of radiotherapy and bromodeoxyuridine with radiotherapy alone for brain metastases: Report of RTOG trial 89-05. Int J Radiat Oncol Biol Phys, 33:339-348, 1995.

Sneed PK, Lamborn KR, Larson DA, Prados MD, Malec MK, McDermott MW, Weaver KA, Phillips TL, Wara WM, Gutin PH. Demonstration of brachytherapy boost dose response relationships in glioblastoma multiforme. Int J Radiat Oncol Biol Phys, 35:37-44, 1996.

Diederich CJ, Khalil IS, Stauffer PR, Sneed PK, Phillips TL. Direct coupled interstitial ultrasound applicators for simultaneous thermobrachytherapy: a feasibility study. Int J Hyperthermia, 12:401-419, 1996.

Roach M, Meehan S, Kroll S, Weil M, Ryu J, Small EJ, Margolis LW, Presti J, Carroll PC, Phillips TL. Radiotherapy for high grade clinically localized adenocarcinoma of the prostate. J Urology, 156:1719-1723, 1996.

Sneed PK, Russo C, Scharfen CO, Prados M, Malec MK, Larson DA, Lamborn KR, Lamb SA, Voss B, Weaver KA, Phillips TL, Gutin PH, Wara WM, Edwards MSB. Long-term follow-up after high activity 125-I brachytherapy for pediatric brain tumors. Pediatric Neurosurgery, 24:314-322, 1996.

Gaspar L, Scott C, Rotman M, Asbell S, Phillips T, Wasserman T, McKenna WG, Byhardt R. Recursive partitioning analysis (RPA) of prognostic factors in three Radiation Therapy Oncology Group (RTOG) brain metastases trials. Int J Radiat Oncol Biol Phys, 37:745-751, 1997.

Swift PS, Purser P, Roberts LW, Pickett B, Powell B, Phillips TL. Pulsed low dose rate brachytherapy for pelvic malignancies. Int J Radiat Oncol Biol Phys, 37:811-817, 1997.

Castro JR, Phillips TL, Prados M, Gutin P, Larson DA, Petti P, Daftari IK, Collier JM, Lillis-Hearne P. Neon heavy charged particle radiotherapy of glioblastoma of the brain. Int J Radiat Oncol Biol Phys, 38:257-261, 1997.

Castro JR, Char DH, Petti PL, Daftari IK, Quivey JM, Singh RP, Blakely EA, Phillips TL. 15 years experience with helium ion radiotherapy for uveal melanoma. Int J Radiat Oncol Biol Phys, 39:989-996, 1997.

Le QT, Fu KF, Kroll S, Ryu JK, Quivey JM, Meyler TS, Krieg RM, Phillips TL. Influence of fraction size, total dose, and overall time on local control of T1-T2 glottic carcinoma. Int J Radiat Oncol Biol Phys, 39:115-127, 1997.

Phillips TL, Ross GY. Effects of ctyotoxic chemotherapy agents on split-dose repair in intestinal crypt cells. Int J Radiat Oncol Biol Phys, 39:817-822, 1997.

Prados MD, Larson DA, Lamborn K, McDermott M, Sneed PK, Wara WM, Chang SM, Mack EE, Krouwer HGJ, Chandler KL, Warnick RE, Davis RL, Rabbitt JE, Malec M, Levin VA, Gutin PH, Phillips TL, Wilson CB. Radiation therapy and hydroxyurea followed by the combination of 6-thioguanine and BCNU for the treatment of primary malignant brain tumors. Int J Radiat Oncol Biol Phys, 40:57-63, 1997.

Chu WT, Bleuel DL, Donahue RJ, Gough RA, Hoff MD, Kwan J, Leung KN, Ludewight BA, Peters C, Phillips TL, Reginato LL, Staples JW, Wells RP, Yu SS. Design of a new BNCT facility based on an ESQ accelerator. Advances in Neutron Therapy, 1:533-537, 1997.

Sneed PK, Stauffer PR, McDermott MW, Diederich CJ, Lamborn KR, Prados MD, Chang S, Weaver KA, Spry L, Malec MK, Lamb SA, Voss B, Davis RL, Wara WM, Larson DA, Phillips TL, Gutin PH. Survival benefit of hyperthermia in a prospective randomized trial of brachytherapy boost ± hyperthermia for glioblastoma multiforme. Int J Radiat Oncol Biol Phys, 40:287-295, 1998.

Prados MD, Scott CB, Rotman M, Rubin P, Murray K, Sause W, Asbell S, Comis R, Curran W, Nelson J, Davis RL, Levin VA, Lamborn K, Phillips TL. Influence of bromodeoxyuridine radiosensitization on malignant glioma patient survival: A retrospective comparison of survival data from the Northern California Oncology Group (NCOG) and Radiation Therapy Oncology Group Trials (RTOG) for glioblastoma multiforme and anaplastic astrocytoma. Int J Radiat Oncol Biol Phys, 40:653-659, 1998.

Sneed PK, Stauffer PR, McDermott MW, Diederich CJ, Lamborn KR, Prados MD, Chang S, Weaver KA, Spry L, Malec MK, Lamb SA, Voss B, Davis RL, Wara WM, Larson DA, Phillips TL, Gutin PH. Survival benefit of hyperthermia in a prospective randomized trial of brachytherapy boost ± hyperthermia for glioblastoma multiforme. Int J Radiat Oncol Biol Phys, 40:287-295, 1998.

Prados MD, Scott CB, Rotman M, Rubin P, Murray K, Sause W, Asbell S, Comis R, Curran W, Nelson J, Davis RL, Levin VA, Lamborn K, Phillips TL. Influence of bromodeoxyuridine radiosensitization on malignant glioma patient survival: A retrospective comparison of survival data from the Northern California Oncology Group (NCOG) and Radiation Therapy Oncology Group Trials (RTOG) for glioblastoma multiforme and anaplastic astrocytoma. Int J Radiat Oncol Biol Phys, 40:653-659, 1998.

Seung S, Sneed PK, McDermott MW, Shu HK, Leong SP, Chang S, Petti PL, Smith V, Verhey LJ, Wara WM, Phillips TL, Larson DA. Gamma Knife radiosurgery for malignant melanoma brain metastases. Cancer J Sci Am 1998; 4:103-109, 1998.

Hwang JM, Fu KK, Phillips TL. Results and prognostic factors in the re-treatment of locally recurrent nasopharyngeal carcinoma. Int J Radiat Oncol Biol Phys,41(5)1099-111, 1998.

Seaward SA, Weinber V, Lewis P,Leigh B,Phillips TL,Roach M. Improved freedom from PSA failure with whole pelvis irradiation for high risk prostate cancer. Int. J Radiat Oncol Biol Phys 42(50 1055-62, 1998.

Seaward SA, Weinber V, Lewis P, Leigh B, Phillips TLRoach M. Identification of High Risk clinically localized Prostate Cancer subgroup receiving maximum benefit from whole-pelvic irradiation. Cancer Journal from Scientific American 4(6):370-7, 1998.

Sneed PK, Lamborn KR, Forstner JM, McDermott MW, Chang S, Park E, Gutin PH, Phillips TL, Wara WM, Larson DA. Radiosurgery for brain metastases: Is whole brain radiotherapy necessary?. Int J Radiat Oncol Biol Phys, 43(3):549-558, 1999.

Grigsby PW, Winter K, Wasserman TH, Marcial V, Rotman M, Cooper J, Keys H, Asbell SO, Phillips TL. Irradiation with or without misonidazole for patients with stages IIIb and IVA carcinoma of the cervix: Final results of RTOG 80-05. Int J Radiat Oncol Biol Phys, 44, 3: 513-517, 1999.

Char DH, Irvine AI, Posner MD, Quivey J, Phillips TL, Kroll S. Randomized Trial of radiation for age related macular degeneration. Am. J. Ophthalmology, 127(5): 574-8, 1999.

Fu KK, Pajak TF, Trotti A, Jones CU, Spencer SA, Phillips TL, Garden AS, Ridge JA, Cooper JS Ang KK. A Radiation Therapy Oncology Group (RTOG) randomized study to compare hyperfractionation and two variants of accelerated fractionation to standard fractionation radiotherapy for head and neck squamous cell carcinomas: first report of RTOG 9003. Int J Radiat Oncol Biol Phys. 48(1): 7-16, 2000.

Shu HK, Lee TT, Vigneau E, Xia P, Pickett B, Phillips TL, Roach M. Toxicity following high-dose three dimensional conformal and intensity modulated radiation therapy for clinically localized prostate cancer. Urology. 2001 Jan;57(1):102-7.

Prados MD, Wara WM, Phillips TL et al. Phase III trial of accelerated hyperfractionation with or without difluromethyl ornithine (DFMO) versus standard fractionated radiotherapy with or without DFMO for newly diagnosed patients with glioblastoma multiforme. Int J Radiat Oncol Biol Phys 2001 Jan 1:49(1):71-7.