Dr. Patricia (Penny) K. Sneed is a radiation oncologist with a special interest in the treatment of breast and brain cancer. She also researches new treatments for these conditions, specifically using the gamma knife. Sneed is the recipient of numerous awards, including the Fellowship in the American College of Radiology. She earned her medical degree from Stanford University and completed a residency in radiation oncology at the University of California, San Francisco. She is a Professor in Residence in the department of Radiation Oncology at UCSF.
Awards & Honors
Recent Significant Publications
Sperduto PW, Kased N, Roberge D, Chao ST, Shanley R, Luo X, Sneed PK, Suh J, Weil RJ, Jensen AW, Brown PD, Shih HA, Kirkpatrick J, Gaspar LE, Fiveash JB, Chiang V, Knisely JP, Sperduto CM, Lin N, Mehta M. The effect of tumor subtype on the time from primary diagnosis to development of brain metastases and survival in patients with breast cancer. J Neurooncol. 2013 Mar 6.
Davies JM, Trinh VT, Sneed PK, McDermott MW. Radiotherapy for recurrent epidermoid cyst. J Neurooncol. 2013 Apr;112(2):307-13.
Ma L, Sahgal A, Nie K, Hwang A, Karotki A, Wang B, Shrieve DC, Sneed PK, McDermott M, Larson DA. Reliability of contour-based volume calculation for radiosurgery. J Neurosurg. 2012 Dec;117 Suppl:203-10.
Fogh S, Ma L, Gupta N, Sahgal A, Nakamura JL, Barani I, Sneed PK, McDermott M, Larson DA. High-precision volume-staged Gamma Knife surgery and equivalent hypofractionation dose schedules for treating large arteriovenous malformations. J Neurosurg. 2012 Dec;117 Suppl:115-9.
Sperduto PW, Sneed PK, Roberge D, Shanley R, Luo X, Luo X, Weil RJ, Suh J, Bhatt A, Jensen AW, Brown PD, Shih HA, Kirkpatrick J, Gaspar LE, Fiveash JB, Knisely JP, Lin N, Mehta M.In regard to Yamamoto et al. Int J Radiat Oncol Biol Phys. 2012 Nov 15;84(4):875-6; discussion 876-7.
Sperduto PW, Kased N, Roberge D, Xu Z, Shanley R, Luo X, Sneed PK, Chao ST, Weil RJ, Suh J, Bhatt A, Jensen AW, Brown PD, Shih HA, Kirkpatrick J, Gaspar LE, Fiveash JB, Chiang V, Knisely JP, Sperduto CM, Lin N, Mehta M. Summary report on the graded prognostic assessment: an accurate and facile diagnosis-specific tool to estimate survival for patients with brain metastases. J Clin Oncol. 2012 Feb 1;30(4):419-25.
Caballero JA, Sneed PK, Lamborn KR, Ma L, Denduluri S, Nakamura JL, Barani IJ, McDermott MW. Prognostic factors for survival in patients treated with stereotactic radiosurgery for recurrent brain metastases after prior whole brain radiotherapy. Int J Radiat Oncol Biol Phys. 2012 May 1;83(1):303-9.
Ma L, Sahgal A, Hwang A, Hu W, Descovich M, Chuang C, Barani I, Sneed PK, McDermott M, Larson DA. A two-step optimization method for improving multiple brain lesion treatments with robotic radiosurgery. Technol Cancer Res Treat. 2011 Aug;10(4):331-8.
Sperduto PW, Kased N, Roberge D, Xu Z, Shanley R, Luo X, Sneed PK, Chao ST, Weil RJ, Suh J, Bhatt A, Jensen AW, Brown PD, Shih HA, Kirkpatrick J, Gaspar LE, Fiveash JB, Chiang V, Knisely JP, Sperduto CM, Lin N, Mehta M. Effect of tumor subtype on survival and the graded prognostic assessment for patients with breast cancer and brain metastases. Int J Radiat Oncol Biol Phys. 2012 Apr 1;82(5):2111-7.
Descovich M, Sneed PK, Barbaro NM, McDermott MW, Chuang CF, Barani IJ, Nakamura JL, Lijun M.A dosimetric comparison between Gamma Knife and CyberKnife treatment plans for trigeminal neuralgia. J Neurosurg. 2010 Dec;113 Suppl:199-206.
Kano H, Iqbal FO, Sheehan J, Mathieu D, Seymour ZA, Niranjan A, Flickinger JC, Kondziolka D, Pollock BE, Rosseau G, Sneed PK, McDermott MW, Lunsford LD. Stereotactic radiosurgery for chordoma: a report from the North American Gamma Knife Consortium. Neurosurgery. 2011 Feb;68(2):379-89.
Sperduto PW, Chao ST, Sneed PK, Luo X, Suh J, Roberge D, Bhatt A, Jensen AW, Brown PD, Shih H, Kirkpatrick J, Schwer A, Gaspar LE, Fiveash JB, Chiang V, Knisely J, Sperduto CM, Mehta M. Diagnosis-specific prognostic factors, indexes, and treatment outcomes for patients with newly diagnosed brain metastases: a multi-institutional analysis of 4,259 patients. Int J Radiat Oncol Biol Phys. 2010 Jul 1;77(3):655-61.
Kased N, Binder DK, McDermott MW, Nakamura JL, Huang K, Berger MS, Wara WM, Sneed PK. Gamma Knife radiosurgery for brain metastases from primary breast cancer. Int J Radiat Oncol Biol Phys. 2009 Nov 15;75(4):1132-40.
Prados MD, Chang SM, Butowski N, DeBoer R, Parvataneni R, Carliner H, Kabuubi P, Ayers-Ringler J, Rabbitt J, Page M, Fedoroff A, Sneed PK, Berger MS, McDermott MW, Parsa AT, Vandenberg S, James CD, Lamborn KR, Stokoe D, Haas-Kogan DA. Phase II study of erlotinib plus temozolomide during and after radiation therapy in patients with newly diagnosed glioblastoma multiforme or gliosarcoma. J Clin Oncol. 2009 Feb 1;27(4):579-84.
Barajas RF, Chang JS, Sneed PK, Segal MR, McDermott MW, Cha S. Distinguishing recurrent intra-axial metastatic tumor from radiation necrosis following gamma knife radiosurgery using dynamic susceptibility-weighted contrast-enhanced perfusion MR imaging. AJNR Am J Neuroradiol. 2009 Feb;30(2):367-72.
Huang K, Sneed PK, Kunwar S, Kragten A, Larson DA, Berger MS, Chan A, Pouliot J, McDermott MW. Surgical resection and permanent iodine-125 brachytherapy for brain metastases. J Neurooncol. 2009 Jan;91(1):83-93.
Kased N, Huang K, Nakamura JL, Sahgal A, Larson DA, McDermott MW, Sneed PK. Gamma Knife radiosurgery for brainstem metastases: the UCSF experience. Journal of Neuro-Oncology 86(2):195-205, 2008.
Golden DW, Lamborn KR, McDermott MW, Kunwar S, Wara WM, Nakamura JL, Sneed PK. Prognostic factors and grading systems for overall survival in patients treated with radiosurgery for brain metastases: variation by primary site. J Neurosurg. 2008 Dec;109 Suppl:77-86.
Melisko ME, Moore DH, Sneed PK, DeFranco J, Rugo HS. Brain metastases in breast cancer: clinical and pathological characteristics associated with improvements in survival. J Neurooncol. 2008 Jul;88(3):359-6.
Smith JS, Parney IF, Lamborn KR, McDermott MW, Sneed PK, Chang SM. Treatment for posterior fossa dissemination of primary supratentorial glioma. Journal of Neurosurgery 106(4):567-74, 2007.
Chen AM, Chang S, Pouliot J, Sneed PK, Prados MD, Lamborn KR, Malec MK, McDermott MW, Berger MS, Larson DA. Phase I trial of gross total resection, permanent iodine-125 brachytherapy, and hyperfractionated radiotherapy for newly diagnosed glioblastoma multiforme. International Journal of Radiation Oncology, Biology, Physics 69(3):825-30, 2007.
Dagnew E, Kanski J, McDermott MW, Sneed PK, McPherson C, Breneman JC,Warnick RE. Management of newly diagnosed single brain metastasis using resection and permanent iodine-125 seeds without initial whole-brain radiotherapy: a two institution experience. Neurosurgical Focus 22(3):E3, 2007.