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• About

Professional Focus

Dr. Verhey is Professor Emeritus of Radiation Oncology. He was the Chief of the Division of Physics from 1993 until 2008. His research interests are in the development and implementation of new methods of radiation delivery that can increase the ratio of tumor dose to normal tissue dose. Specifically, this has involved the use of proton beams, stereotactic radiosurgery with the Gamma Knife and Intensity Modulated Radiotherapy (IMRT) using linear accelerators. He is the author or co-author of more than 120 peer-reviewed scientific papers, as well as multiple contributions to proceedings and chapters in technical books.

Education

Professional Experience

Awards & Honors

Publications

Verhey LJ, Smith V, Serago CS. Comparison of radiosurgery treatment modalities based on physical dose distributions. Int. J. Radiat. Oncol. Biol. Phys. 40(2):497-505, 1998.

Smith V, Verhey LJ, Serago CS. Comparison of radiosurgery treatment modalities based on complication and control probabilities. Int. J. Radiat. Oncol. Biol. Phys. 40(2):507-513, 1998.

Xia P, Verhey LJ. MLC leaf sequencing algorithm for intensity modulated beams with multiple static segments. Medical Physics 25(8):1424-1434, 1998.

Verhey, LJ. Comparison of Three-dimensional Conformal Radiation Therapy and Intensity-Modulated Radiation Therapy Systems. Sem. in Rad. Onc. 9(1):78-98, 1999.

Xia P, Fu KK, Wong GW, Akazawa C, Verhey LJ. Comparison of treatment plans involving intensity-modulated radiotherapy for nasopharyngeal carcinoma. Int. J. Radiation Oncology Biol. Phys. 48(2):329-337, 2000.

Graves EE, Nelson SJ, Vigneron DB, Chin C, Verhey L, McDermott M, Larson D, Sneed PK, Chang S, Prados MD, Lamborn K, Dillon WP. A preliminary study of the prognostic value of proton magnetic resonance spectroscopic imaging in gamma knife radiosurgery of recurrent malignant gliomas. Neurosurgery 46(2):319-328, 2000.

Pirzkall A, McKnight TR, Graves EE, Carol MP, Sneed PK, Wara WW, Nelson SJ,Verhey LJ, Larson DA. MR-spectroscopy guided target delineation for high-grade gliomas. Int J Radiat Oncol Biol Phys. 50(4):915-28, 2001.

Hartmann Siantar CL, Walling RS, Daly TP, Faddegon B, Albright N, Bergstrom P, Bielajew AF, Chuang C, Garrett D, House RK, Knapp D, Wieczorek DJ, Verhey LJ. Description and dosimetric verification of the PEREGRINE Monte Carlo dose calculation system for photon beams incident on a water phantom. Med. Phys. 28(7):1322-1337, 2001.

Xia P, Verhey LJ. Delivery systems of intensity-modulated radiotherapy using conventional multileaf collimators. Medical Dosimetry 26(2):169-177, 2001.

Xia P, Pickett B, Vigneault E, Verhey LJ, Roach III M. Forward or inversely planned segmental multileaf collimator IMRT and sequential tomotherapy to treat multiple dominant intraprostatic lesions of prostate cancer to 90 Gy. Int. J. Radiation Oncology Biol. Phys. 51(1):244-254, 2001.

Graves EE, Pirzkall A, Nelson SJ, Verhey LJ, Larson DA. Registration of magnetic resonance spectroscopic imaging to computed tomography for radiotherapy treatment planning. Med. Phys. 28(12):2489-2496, 2001.

Nakamura JL, Verhey LJ, Smith V, Petti PL, Lamborn KR, Larson DA, Wara WM, McDermott MW, Sneed PK. Dose conformity of gamma knife radiosurgery and risk factors for complications. Int. J. Radiation Oncology Biol. Phys. 51(5):1313-1319, 2001.

Pirzkall A, Carol MP, Pickett B, Xia P, Roach III M, Verhey LJ. The effect of beam energy and number of fields on photon-based IMRT for deep-seated targets. Int J Radiat Oncol Biol Phys. 53(2):434-442, 2002.

Lee N, Chuang C, Quivey JM, Phillips TL, Akazawa P, Verhey LJ, Xia P. Skin toxicity due to intensity-modulated radiotherapy for head-and-neck carcinoma. Int. J. Radiation Oncology Biol. Phys. 53(3):630-637, 2002.

Xia P, Chuang CF, Verhey LJ. Communication and sampling rate limitations in IMRT delivery with a dynamic multileaf collimator system. Med. Phys. 29(3): 412-423, 2002.

Xia P, Hwang AB, Verhey LJ. A leaf sequencing algorithm to enlarge treatment field length in IMRT. Med. Phys. 29(6):991-998, 2002.

Chuang CF, Verhey LJ, Xia P. Investigation of the use of MOSFET for clinical IMRT dosimetric verification. Med. Phys. 29(6):1109-1115, 2002.

Verhey LJ. Issues in optimization for planning of intensity-modulated radiation therapy. Seminars in Radiation Oncology 12(3):210-218, 2002.

Pirzkall A, Nelson SJ, McKnight TR, Takahashi MM, Li X, Graves EE, Verhey LJ, Wara WM, Larson DA, Sneed PK. Metabolic imaging of low-grade gliomas with three-dimensional magnetic resonance spectroscopy. Int J Radiat Oncol Phys. 53(5):1254-1264, 2002.

Nakamura JL, Pirzkall A, Carol MP, Xia P, Smith V, Wara WM, Petti PL, Verhey LJ, Sneed PK. Comparison of intensity-modulated radiosurgery with Gamma Knife radiosurgery for challenging skull base lesions. Int. J. Radiation Oncology Biol. Phys. 55(1):99-109, 2003.

Langen KM, Pouliot J, Anezinos C, Aubin M, Gottschalk AR, Hsu I-C, Lowther D, Liu Y-M, Shinohara K, Verhey LJ, Weinberg V, Roach III M. Evaluation of ultrasound-based prostate localization for image-guided radiotherapy. Int J Radiat Oncol Biol Phys. 57(3):635-644, 2003.

Pirzkall A, Li X, Oh J, Chang S, Berger MS, Larson DA, Verhey LJ, Dillon WP, Nelson SJ. 3D MRSI for resected high-grade gliomas before RT: tumor extent according to metabolic activity in relation to MRI. Int J Radiat Oncol Biol Phys. 59(1):126-137, 2004.

Xia P, Lee N, Liu YM, Poon I, Weinberg V, Shin E, Quivey JM, Verhey LJ. A study of planning dose constraints for treatment of nasopharyngeal carcinoma using a commercial inverse treatment planning system. Int J Radiat Oncol Biol Phys 59(3): 886-896, 2004.

Chan AA, Lau A, Pirzkall A, Chang SM, Verhey LJ, Larson D, McDermott MW, Dillon WP, Nelson SJ. Proton magnetic resonance spectroscopic imaging as a tool for evaluating Grade IV glioma patients undergoing gamma knife radiosurgery. J Neurosurg 101(3): 467-475, 2004.

Pouliot J, Bani-Hashemi A, Chen J, Svatos M, Ghelmansarai F, Mitschke M, Aubin M, Xia P, Morin O, Bucci K, Roach III M, Hernandez P, Zheng Z, Hristov D, Verhey L. Low-dose megavoltage cone-beam CT for radiation therapy. Int. J. Radiation Oncology Biol. Phys. 61(2): 552-560, 2005.