Welcome to the Chan Lab website!
Our broad goal is to understand the tumor microenvironment, particularly the mechanisms by which cells sense and respond to hypoxia, or low oxygen conditions. Hypoxia is a hallmark of solid tumors, a consequence of multiple influences...
Follow the link to meet our enthousiastic, hard-working, self-motivated team members.
Since 2002, Dr. Chan has published over 30 publications in the field of Radiobiology.
Dr. Chan became a UCSF Hellman Fellow.
Dr. Chan was awarded a UCSF Program in Breakthrough Biomedical Research Grant.
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Review article in Nature Reviews Drug Discovery - 08/11
Chan DA and Giaccia AJ. Harnessing synthetic lethal interactions in anticancer drug discovery, Nat Rev Drug Discov 10, 351-364, 2011.
In Science Translational Medicine - 08/11
Chan DA, Sutphin PD, Nguyen P, Turcotte S, Lai EW, Banh A, Reynolds GE, Chi JT, Wu J, Solow-Cordero DE, Bonnet M, Flanagan JU, Bouley DM, Graves EE, Denny WA, Hay MP and Giaccia AJ. Targeting GLUT1 and the Warburg effect in renal cell carcinoma by chemical synthetic lethality, Sci Transl Med 3, 94ra70, 2011.