David Raleigh

David Raleigh

David R. Raleigh, M.D., Ph.D

Assistant Professor
Department of Radiation Oncology

University of California, San Francisco
505 Parnassus Avenue, Room L-08
San Francisco, CA 94143
Clinic Phone: 415-353-3675
Fax: 415 353-8679


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Professional Focus

Dr. Raleigh is specialized in the treatment and investigation of central nervous system tumors in adult and pediatric patients. His research focuses on the biologic processes that cause brain tumors to grow. His primary goal is to understand how developmental signaling pathways cause cancer to shed light on the fundamental mechanisms of developmental biology and identify novel treatments for cancer patients. His laboratory research makes use of biochemistry, molecular biology, cell biology, mouse genetics, genomics, bioinformatics and pharmacology to gain new insights into the molecular determinants of human malignancies.

Education

2000-2004 University of California, Berkeley BA (Honors) Molecular and Cell Biology
2000-2004 University of California, Berkeley BA (Honors) Cognitive Science
2005-2012 University of Chicago Medical Doctorate Pritzker School of Medicine
2007-2010 University of Chicago Doctorate of Philosophy Pathology
2005-2012 University of Chicago MD/PhD Student NIH MSTP
2012-2013 Kaiser Permanente Santa Clara Intern Physician Internal Medicine
2013-2017 University of California, San Francisco Resident Physician Radiation Oncology
2015-2016 University of California, San Francisco Chief Resident Physician Radiation Oncology
 

Professional Experience

2017-present University of California, San Francisco Assistant Professor Radiation Oncology
2017-present University of California, San Francisco Principal Investigator Brain Tumor Center
2017-present Children’s Oncology Group Principal Investigator ANBL 1232
 

Awards & Honors

2001-2004 Dean’s Honor Roll, UC Berkeley College of Letters and Science
2004 Graduation with High Honors, UC Berkeley Department of Molecular Cell Biology
2004 Graduation with High Honors, UC Berkeley Department of Cognitive Science
2004 Phi Beta Kappa Inductee, UC Berkeley
2009 Travel Award, FASEB Gastrointestinal Tract XIII Annual Meeting
2009 Poster of Distinction, Digestive Disease Week Annual Meeting
2009 Outstanding Oral Presentation, U Chicago Annual Biomedical Sciences Cluster Retreat
2010 Takeda Travel Award, Experimental Biology Annual Meeting
2011 Top Quartile in Graduating Class, U Chicago Pritzker School of Medicine
2011 Career Development Award, U Chicago Medical Scientist Training Program
2012 Outstanding Performance, U Chicago Department of Radiation and Cellular Oncology
2013 Teaching Award, Kaiser Permanente Santa Clara
2013-2017 ABR Holman Research Pathway, UCSF Department of Radiation Oncology
2015 Resident Research Travel Award, UCSF Clinical & Translational Science Institute
2016 Semi-Finalist, Burroughs Wellcome Fund Medical Scientist Career Award
2016 Roentgen Research Award, Radiological Society of North America
2016 Biology Abstract Travel Award, American Society for Radiation Oncology Annual Meeting
2016 Poster of Distinction, Association of Residents in Radiation Oncology
2016 Top Young Investigator Awardee, ASCO Scientific Career Development Retreat
2016 PSSP Scholar, UCSF Physician Scientist Scholar Program
2017 Young Oncologist Travel Grant, American Radium Society Annual Meeting
2017 Poster of Distinction, American Radium Society Annual Meeting

 

Recent Significant Publications :

Raleigh DR, Algazi A, Arron ST, Neuhaus IM, Yom SS. Induction hedgehog pathway inhibition followed by combination modality radiotherapy for basal cell carcinoma. Br J Dermatol. 2015. 173:544-546. PMID: 25702621.

Oskvarek JJ, Brower JV, Mohindra P, Raleigh DR, Chmura SJ, Golden DW. Educational impact of a structured radiation oncology clerkship curriculum: an inter-institutional comparison. J Am Coll Radiol. 2016. 16: 30632-30639. PMID: 27652570.

Magill ST, Lau D, Raleigh DR, Sneed PK, McDermott MW. Surgical resection and interstitial 125I brachytherapy for high grade meningioma: a 25 year series. Neurosurg. 2017. 80:409-416. PMID: 27258768.

Raleigh DR†, Solomon DA†, Lloyd SA, Lazar A, Garcia MA, Sneed PK, Clarke JL, McDermott MW, Berger MS, Tihan T, Haas-Kogan DA. Histopathologic review of pineal parenchymal tumors identifies novel morphologic subtypes and prognostic factors for outcome. Neuro Oncol. 2017. 19:78-88. PMID: 27282397.

Garcia MA, Lazar A, Duriseti S, Raleigh DR, Hess C, Fogh SE, Barani IJ, Nakamura JL, Larson DA, Theodosopoulos P, McDermott MW, Sneed PK, Braunstein SE. Discovery of additional brain metastases on the day of stereotactic radiosurgery: risk factors and outcomes. J Neurosurg. 2017. 126:1756-1763. PMID: 27367235.

Raleigh DR, Seymour ZA, Tomlin B, Theodosopoulos PV, Berger MS, Aghi MK, Geneser SE, Krishnamurthy D, Fogh SE, Sneed PK, McDermott MW. Resection and brain brachytherapy with permanent iodine-125 seeds for brain metastasis. J Neurosurg. 2017. 126:1749-1755. PMID: 27367240.

Raleigh DR, Tomlin B, Del Buono B, Roddy E, Sear K, Byer L, Felton E, Banerjee A, Torkildson J, Samuel D, Horn B, Braunstein SE, Haas-Kogan DA, Mueller S. Survival after chemotherapy and stem cell transplant followed by delayed craniospinal irradiation is comparable to upfront craniospinal irradiation in pediatric embryonal brain tumor patients. J Neurooncol. 2017. 131:359-368. PMID: 27778212.

Kline CN, Joseph NM, Grenert JP, van Ziffle J, Talevich E, Onodera C, Aboian M, Cha S, Raleigh DR, Braunstein SE, Torkildson J, Samuel D, de Alba Campomanes A, Banerjee A, Butowski N, Raffel C, Tihan T, Bollen AW, Phillips JJ, Korn M, Yeh I, Bastian BC, Gupta N, Mueller S, Perry A, Nicolaides T, Solomon DA. Targeted next-generation sequencing of pediatric brain tumor patients improves diagnosis, identified pathogenic germline mutations, and directs targeted therapy. Neuro Oncol. 2017. 19:699-709. PMID: 27978508.

Braunstein SE†, Raleigh DR†, Bindra R, Mueller S, Haas-Kogan DA. Pediatric high grade gliomas. J Neurooncol. In press.

Vasudevan HN†, Raleigh DR†, Johnson J, Garsa AA, Theodosopoulos PV, Aghi MK, Ames C, McDermott MW, Barani IJ, Braunstein SE. Management of chordoma and chondrosarcoma with fractionated stereoetactic radiotherapy. Neurosurg Focus. In press.