Clinical Trials
Our department is involved with some of the most important and innovative clinical trials in radiation oncology.
Clinical trials give patients access to the most advanced treatments to conquer their cancer and improve their lives. Our team learns about our patients’ needs and develops these new treatments. They are then tested in clinical trials.
Some of the most important trials ever completed in radiation oncology have been led by UCSF doctors. The largest trials in patients with head and neck and prostate cancers were designed and led by our doctors. As a leading research institution, UCSF continues to innovate and run cutting edge clinical trials to improve the lives of our patients with cancer.
Contact for UCSF Radiation Oncology clinical trials:
Jamese Johnson, MPH, CPH
Clinical Research Manager
Department of Radiation Oncology
Helen Diller Family Comprehensive Cancer Center
Email: jamese.johnson@ucsf.edu
Phone: 415-476-3048
Current Trials
Principal Investigator | Study Title | Disease | Status |
---|---|---|---|
Steve Braunstein, MD, PhD |
Ride to careEliminating transportation barriers for disadvantaged cancer patients undergoing RT |
All | Open |
Catherine Park, MD |
FABRECStudy of Radiation Fractionation on Patient Outcomes After Breast Reconstruction for Invasive Breast Carcinoma |
Breast Cancer | Open |
Anthony Wong, MD, PhD |
FORMULA-509Randomized Phase II Study of Salvage XRT + ADT +/- Abiraterone Acetate and Apalutamide (ARN-509) for Rising PSA after Radical Prostatectomy with Adverse Features. Facilitating Optimal Radiation Management |
Prostate Cancer | Closed |
Anthony Wong, MD, PhD |
RTOG 3506STEEL: A Randomized Phase II Trial of Salvage Radiotherapy with Standard vs Enhanced Androgen Deprivation Therapy (with Enzalutamide) in Patients with Post-Prostatectomy PSA Recurrences with Aggressive Disease Features |
Prostate Cancer | Open |
Osama Mohamad, MD, PhD |
GU 008Randomized Phase III Incorporating Abiraterone Acetate with Prednisone and Apalutamide and Advanced Imaging into Salvage Treatment for Patients with Node-Positive Prostate Cancer After Radical Prostatectomy |
Prostate Cancer | Opening early 2021 |
Sue Yom, MD, PHD |
NRG-HN001Randomized Phase II and Phase III Studies of Individualized Treatment for Nasopharyngeal Carcinoma Based on Biomarker Epstein Barr Virus (EBV) Deoxyribonucleic Acid (DNA). |
Head & Neck Cancer | Open |
Sue Yom, MD, PhD |
Nivolumab + ChemoRT for Patients with Nasopharyngeal Cancer |
Nasopharyngeal Cancer | Open |
Sue Yom, MD, PhD |
A Phase 1/2 Trial of Concurrent RT, Cisplatin, and BMX-001 in Locally Advanced Head and Neck Cancer |
Head and Neck Cancer | Open |
Sue Yom, MD, PhD |
HN004Randomized Phase II/III Trial of Radiotherapy with Concurrent MEDI4736 (Durvalumab) vs. Radiotherapy with Concurrent Cetuximab in Patients with Locoregionally Advanced Head and Neck Cancer with a Contraindication to Cisplatin |
Head and Neck Cancer | Open |
Sue Yom, MD, PhD |
HN005A Randomized Phase II/III Trial of De-Intensified Radiation Therapy for Patients with Early-Stage, p16-Positive, Non-Smoking Associated Oropharyngeal Cancer |
Head and Neck Cancer | Open |
Sue Yom, MD, PhD |
PembroXEnhancing the Immunogenicity of Non-Small Cell Lung Cancer with Pembrolizumab +/- Stereotactic Radiotherapy Delivered in the Preoperative Window, A Randomized Phase II Study with Correlative Biomarkers |
Lung Cancer | Open |
Steve Braunstein, MD, PhD |
METISPivotal, open-label, randomized study of radiosurgery with or without Tumor Treating Fields (TTFields) for 1-10 brain metastases from non-small cell lung cancer (NSCLC) |
Lung Cancer | Open |
Sue Yom, MD, PhD |
RTOG 1216Randomized Phase II/III Trial of Adjuvant Radiation Therapy with Cisplatin, Docetaxel-Cetuximab, or Cisplatin-Atezolizumab in Pathologic High-Risk Squamous Cell Cancer of the Head and Neck |
Head and Neck Cancer | Open |
Mary Feng, MD |
ARM-GIPhase II study of hypofractionated radiation therapy to Augment immune Response in patients with Metastatic GastroIntestinal malignancies progressing on immune therapy |
GI cancers | Open |
Mary Feng, MD |
Phase II TrialPalliative Hypofractionated Radiotherapy Followed by Durvalumab (MEDI4736) with/without Tremelimumab for Advanced Hepatocellular Carcinoma after Progression on Prior PD-1 Inhibition |
Liver Cancer | Opening early 2021 |
Mary Feng, MD |
DECREASEA Randomized Phase II Study of De-Intensified ChemoRadiation for Early-Stage Anal Squamous Cell Carcinoma |
Anal cancer | Opening early 2021 |
For more information about clinical trials: http://www.clinicaltrials.gov/ct/info/whatis#whatis